The department conducts trials on drugs, diagnostics and vaccines for Tuberculosis (TB), HIV, Malaria and other diseases including respiratory pathogens, zoonotic diseases, arboviruses, and various emerging and re-emerging infections. The department is supported by two laboratories with state of the art facilities at Ifakara and Bagamoyo Branches. The department is also expanding its portfolio to include non-communicable diseases, which are on the rise even in developing countries. Though we were previously working mostly on malaria, we have in recent years began work on development and testing of new TB drugs, given that what we have today have been in use for over 50 years. At our Chronic Diseases Clinic in Ifakara, we offer high quality HIV clinical care, while at the same time training researchers to improve the clinical care of HIV-infected people. Moreover, IHI laboatories are continuously improving the diagnostic capacity, to serve IHI research projects and collaborators both within and outside the country. Our immunology department has grown in human capacity and equipment to analyze samples for different TB and malaria clinical trials.
In recent years scientists in the department have pioneered multiple innovative ways to assess vaccine candidates on malaria challenge study with infectious sporozoites. We are currently also providing technical support in other countries to start and implementing clinical trials. For example, we have a group now based in Equitorial Guinea supporting large-scale vaccine trial programs there. The department strives to strengthen the capacity to conduct clinical trials on infectious diseases including training IHI staff at Masters and PhD level. IHI is now firmly established as a dependable site where trials could be conducted in the future. The department staff are multidisplinary, consisting of statisticians, physicians, epidemiologists, public health specialists and social scientists.