Assessing the progress towards rabies elimination...

In the News

Muhas don is new IHI board member

Prof. Kaaya. Ifakara Health Institute (IHI) Board of Governors (BOG) has appointed Prof. Sylvia Kaaya member of the IHI Board of Trustees (BOT) effective Wednesday January 10, 2018. The appointment …

Marcel steps down from IHI boards

Prof. Marcel Tanner has stepped down as Ifakara Health Institute (IHI) member of the Board of Trustees (BOT) and Board of Governors (BOG) effective Wednesday January 10, 2018. The Former …

Recent Projects

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Demonstrating complete disruption of residual malaria transmission by eliminating Anopheles funestus mosquitoes from rural Tanzanian villages

In rural south-eastern Tanzania, where malaria prevalence has reduced by >60% since 2000, low-to-moderate transmission still persists despite very high coverage with long-lasting insecticidal bednets. Like in most residual transmission …

Assessing the progress towards rabies elimination from Pemba Island, Tanzania

Rabies is a deadly disease endemic in dog populations across Africa. Although rabies can be eliminated through mass dog vaccination, there has been little investment in dog vaccination in Africa and there are few examples of local disease elimination on the continent. Recently the Tanzanian government embarked on a large-scale rabies elimination demonstration programme in Southern Tanzania based on annual mass dog vaccinations. As part of this programme three campaigns have been conducted on the island of Pemba (approximately 4000 dogs), yet rabies still persists in this isolated population. This study aims to identify causes of persistent foci of infection and determine what factors affect the time to eliminate such foci from Pemba, addressing the following questions: a) Where are foci of infection persisting on Pemba?, b) What factors enable disease persistence? and c) if rabies is eliminated from Pemba, how rapidly were foci eliminated and what factors determined time to elimination? Detailed contact tracing tracking localized rabies transmission are used to identify persistent foci of infection on the island. Survey data on dog ownership, data from vaccination campaigns and geographical data on landscape features and the distribution of the dog population are also compiled. Using these data, factors associated with persistent infection and the time to eliminate these foci will be identified. Pin-pointing the causes of persistence and determining the effort needed to eliminate rabies from a small island such as Pemba is important for demonstrating the practicality of elimination in African settings. Detailed description of challenges to rabies elimination will provide guidance for future programmes in Africa.

Lead Scientists:

Kennedy Lushasi


University of Glasgow


Wellcome Trust

Projects Location

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