Screening and treatment of cryptococcal meningitis...

In the News

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Recent Projects

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The Sustainable, Healthy, Learning Cities and Neighbourhoods is an exciting project in which IHI works with a consortium of partners from Asia and Africa to 1) develop capacity for improved …

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Screening and treatment of cryptococcal meningitis in Kilombero and Ulanga districts in Tanzania

This is a multi-site randomized trial of sertraline and high-dose Fluconazol for the treatment of cryptococcal meningitis. Patients are randomized into conventional treatment with Amphotericin B, Fluconazol and Sertraline versus Amphotericin B and Fluconazol. Ifakara did not initially start randomization but remained with an open-label design, specifically focusing on the question of added value of Sertraline to Fluconazol. In a second protocol, designed as a recruitment study for ASTRO, CRASK (Cryptococcal Antigen Screening Kilombero) screens patients from the peripheral CTCs with a easy to perform Antigen tests and refers them to Ifakara for further diagnostics and treatment within ASTRO in case of proof of cryptococcal meningitis.

This study expands access to diagnosis and treatment of cryptococcal meningitis, one of the major causes of death among people living with HIV.

Lead scientists:

Maja Weisser

Andrew Katende

Partners

Meningitis Research Foundation (MRF)
Makerere University, Kampala, Uganda
University of Minnesota, MN, USA

Funders

Meningitis Research Foundation (MRF)

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016