Screening and treatment of cryptococcal meningitis...

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IHI, partners unveil new malaria control technology

Principal Investigator (PI) of the project, Dr. Ladslaus Mnyone, briefs the media on the sidelines of the dissemination meeting in Dar es Salaam today. PHOTO/JOSEPH MADATA (Dar es Salaam) Ifakara …

Ex-First Lady Salma Kikwete among MPs visiting IHI

Former First Lady Salma Kikwete with other members of the Bunge Committee on HIV/Aids Affairs and Drug Abuse when they visited Kilombero District Commissioner’s office to pay a courtesy call. …

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Screening and treatment of cryptococcal meningitis in Kilombero and Ulanga districts in Tanzania

This is a multi-site randomized trial of sertraline and high-dose Fluconazol for the treatment of cryptococcal meningitis. Patients are randomized into conventional treatment with Amphotericin B, Fluconazol and Sertraline versus Amphotericin B and Fluconazol. Ifakara did not initially start randomization but remained with an open-label design, specifically focusing on the question of added value of Sertraline to Fluconazol. In a second protocol, designed as a recruitment study for ASTRO, CRASK (Cryptococcal Antigen Screening Kilombero) screens patients from the peripheral CTCs with a easy to perform Antigen tests and refers them to Ifakara for further diagnostics and treatment within ASTRO in case of proof of cryptococcal meningitis.

This study expands access to diagnosis and treatment of cryptococcal meningitis, one of the major causes of death among people living with HIV.

Lead scientists:

Maja Weisser

Andrew Katende

Partners

Meningitis Research Foundation (MRF)
Makerere University, Kampala, Uganda
University of Minnesota, MN, USA

Funders

Meningitis Research Foundation (MRF)

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016