Safety and immunogenicity of direct venus...

In the News

Laboratory technician is required

Ifakara Health Institute (IHI) is looking for a laboratory technician to work with NC. TB – DAR project in Bagamoyo.The candidate will perform routine experimental laboratory test- mainly in the …

Field Supervisors required

IHI is looking for Field supervisors to fill a vacant positions in a new project on “Calcium supplementation in pregnant women” The Field supervisor will supervise all field activities at …

Recent Projects

Sustainable, Healthy, Learning Cities and Neighbourhoods

The Sustainable, Healthy, Learning Cities and Neighbourhoods is an exciting project in which IHI works with a consortium of partners from Asia and Africa to 1) develop capacity for improved …

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Clinical Trial to Evaluate the Safety and Immunogenicity in Age De-Escalation of Direct Venous Inoculation of a Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults, Children, and Infants

A single center, double blind, randomized, normal saline placebo-controlled trial of PfSPZ vaccine OR PfSPZ challenge, administered by Direct Venous Inoculation (DVI). The trial is aimed at evaluating safety, tolerability and vaccine-induced humoral and cellular immune responses of PfSPZ Vaccine in healthy male and female Tanzanian adults, adolescents, children, and infants (from 6 months old) who receive doses of 1.8×10⁶, 9.0×10⁵,  4.5×10⁵ or 2.7×10⁵ PfSPZ of PfSPZ and to assess efficacy in adults three weeks and twenty four weeks following immunization using Controlled Human Malaria Infection (CHMI). A total of 105 subjects will be enrolled at the trial completion

Lead Scientists:

Said Jongo

Salim Abdulla

Partners

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Funders

The government of Equitorial Guinea, Marathon Oil, Noble Energy and AMPCO

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016