Safety and immunogenicity of direct venus...

In the News

Chief Operation Officer – COO required at IHI

(Dar es Salaam) IHI is looking for an experienced individual to take the position of Chief Operating Officer (COO). Reporting to the Chief Executive Director (CED), the COO will play …

IHI hosts WaSH collaborators from South Africa

(Dar es Salaam) South Africa’s collaborators in the Leading Integrated Research for Agenda (LIRA) 2030 project visited Ifakara Health Institute (IHI) and a number of sites where the project is …

Recent Projects

Sustainable, Healthy, Learning Cities and Neighbourhoods

The Sustainable, Healthy, Learning Cities and Neighbourhoods is an exciting project in which IHI works with a consortium of partners from Asia and Africa to 1) develop capacity for improved …

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Clinical Trial to Evaluate the Safety and Immunogenicity in Age De-Escalation of Direct Venous Inoculation of a Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults, Children, and Infants

A single center, double blind, randomized, normal saline placebo-controlled trial of PfSPZ vaccine OR PfSPZ challenge, administered by Direct Venous Inoculation (DVI). The trial is aimed at evaluating safety, tolerability and vaccine-induced humoral and cellular immune responses of PfSPZ Vaccine in healthy male and female Tanzanian adults, adolescents, children, and infants (from 6 months old) who receive doses of 1.8×10⁶, 9.0×10⁵,  4.5×10⁵ or 2.7×10⁵ PfSPZ of PfSPZ and to assess efficacy in adults three weeks and twenty four weeks following immunization using Controlled Human Malaria Infection (CHMI). A total of 105 subjects will be enrolled at the trial completion

Lead Scientists:

Said Jongo

Salim Abdulla

Partners

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Funders

The government of Equitorial Guinea, Marathon Oil, Noble Energy and AMPCO

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016