Control of malaria vectors by the...

In the News

Vacancy: Innovation Hub Director (1)

The Ifakara Innovation Hub is looking for a qualified individual to take the post of Innovation Hub Director. The ideal candidate is someone who has the right mix of leadership, …

Vacancy: Environmental Scientist required (1 post)

(Dar es Salaam, July 23 2019) IHI is looking for an experienced Environmental Scientist with analytical chemistry skills to join the Bohemia project team around November/December this year. Please note …

Recent Projects

Calcium supplementation on pregnant women

Project summary This is a trial-based study funded by the Bill and Melinda Gates Foundation. It intends to generate evidence for decision-making on the potential non-inferiority of a lower dose …

Sustainable, Healthy, Learning Cities and Neighbourhoods

The Sustainable, Healthy, Learning Cities and Neighbourhoods is an exciting project in which IHI works with a consortium of partners from Asia and Africa to 1) develop capacity for improved …

Control of malaria vectors by the auto-dissemination of insecticides

Long lasting Insecticide treated nets (LLINs) and Indoor Residual Spraying (IRS) have contributed significantly to reduction of malaria burden over the past decade. However, for elimination of this disease, complementary vector control tools are continuously needed to speed up this process. We believe that mosquitoes themselves could be used to pick up small doses of insecticides and transfer these to their own breeding habitats, and this way, we can stop further proliferation of mosquito populations. This process is called Auto-dissemination. The main goal of the project is to demonstrate utility of auto-dissemination of insecticides for reducing abundance of malaria vectors. The experiments are conducted inside semi-field systems (SFS), designed to mimic natural mosquito ecosystems. The candidate insecticide is Pyriproxyfen (PPF), a juvenile hormone analogue that inhibits normal growth in mosquito life stages, but also sterilizes adult mosquitoes. If delivered effectively to the malaria vectors breeding habitats, most mature juvenile mosquito stages will not become adults, and thus the density of mosquitoes will be reduced, consequently reducing malaria transmission. Our model mosquito is Anopheles arabiensis, a common vector in many residual malaria transmission settings in Africa.

Lead Scientists:

Fredros Okumu

Dickson Wilson Lwetoijera

Samson Kiware

Mercy Opiyo

 

Partners

Liverpool School of Tropical Medicine

Funders

Bill and Melinda Gates Foundation

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016