Control of malaria vectors by the...

In the News

Muhas don is new IHI board member

Prof. Kaaya. Ifakara Health Institute (IHI) Board of Governors (BOG) has appointed Prof. Sylvia Kaaya member of the IHI Board of Trustees (BOT) effective Wednesday January 10, 2018. The appointment …

Marcel steps down from IHI boards

Prof. Marcel Tanner has stepped down as Ifakara Health Institute (IHI) member of the Board of Trustees (BOT) and Board of Governors (BOG) effective Wednesday January 10, 2018. The Former …

Recent Projects

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Demonstrating complete disruption of residual malaria transmission by eliminating Anopheles funestus mosquitoes from rural Tanzanian villages

In rural south-eastern Tanzania, where malaria prevalence has reduced by >60% since 2000, low-to-moderate transmission still persists despite very high coverage with long-lasting insecticidal bednets. Like in most residual transmission …

Control of malaria vectors by the auto-dissemination of insecticides

Long lasting Insecticide treated nets (LLINs) and Indoor Residual Spraying (IRS) have contributed significantly to reduction of malaria burden over the past decade. However, for elimination of this disease, complementary vector control tools are continuously needed to speed up this process. We believe that mosquitoes themselves could be used to pick up small doses of insecticides and transfer these to their own breeding habitats, and this way, we can stop further proliferation of mosquito populations. This process is called Auto-dissemination. The main goal of the project is to demonstrate utility of auto-dissemination of insecticides for reducing abundance of malaria vectors. The experiments are conducted inside semi-field systems (SFS), designed to mimic natural mosquito ecosystems. The candidate insecticide is Pyriproxyfen (PPF), a juvenile hormone analogue that inhibits normal growth in mosquito life stages, but also sterilizes adult mosquitoes. If delivered effectively to the malaria vectors breeding habitats, most mature juvenile mosquito stages will not become adults, and thus the density of mosquitoes will be reduced, consequently reducing malaria transmission. Our model mosquito is Anopheles arabiensis, a common vector in many residual malaria transmission settings in Africa.

Lead Scientists:

Fredros Okumu

Dickson Wilson Lwetoijera

Samson Kiware

Mercy Opiyo



Liverpool School of Tropical Medicine


Bill and Melinda Gates Foundation

Projects Location

© Ifakara Health Institute (IHI), 2016