Control of malaria vectors by the...

In the News

Study establishes link between gender, extramarital affairs and HIV

Dar es Salaam. A new Ifakara Health Institute study has found “a significant association between lifetime (proxy) extramarital affairs and HIV infection among women only,” with the risk being significantly …

IHI names winners of research, innovation fund

[Right-Left] Getrud, Beatrice, Theckla, and Tutu.Ifakara Health Institute (IHI) has named recipients of the 2017/18 Director’s Research and Innovation Fund. This is an internal funding mechanism aimed to support specific …

Recent Projects

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Demonstrating complete disruption of residual malaria transmission by eliminating Anopheles funestus mosquitoes from rural Tanzanian villages

In rural south-eastern Tanzania, where malaria prevalence has reduced by >60% since 2000, low-to-moderate transmission still persists despite very high coverage with long-lasting insecticidal bednets. Like in most residual transmission …

Control of malaria vectors by the auto-dissemination of insecticides

Long lasting Insecticide treated nets (LLINs) and Indoor Residual Spraying (IRS) have contributed significantly to reduction of malaria burden over the past decade. However, for elimination of this disease, complementary vector control tools are continuously needed to speed up this process. We believe that mosquitoes themselves could be used to pick up small doses of insecticides and transfer these to their own breeding habitats, and this way, we can stop further proliferation of mosquito populations. This process is called Auto-dissemination. The main goal of the project is to demonstrate utility of auto-dissemination of insecticides for reducing abundance of malaria vectors. The experiments are conducted inside semi-field systems (SFS), designed to mimic natural mosquito ecosystems. The candidate insecticide is Pyriproxyfen (PPF), a juvenile hormone analogue that inhibits normal growth in mosquito life stages, but also sterilizes adult mosquitoes. If delivered effectively to the malaria vectors breeding habitats, most mature juvenile mosquito stages will not become adults, and thus the density of mosquitoes will be reduced, consequently reducing malaria transmission. Our model mosquito is Anopheles arabiensis, a common vector in many residual malaria transmission settings in Africa.

Lead Scientists:

Fredros Okumu

Dickson Wilson Lwetoijera

Samson Kiware

Mercy Opiyo

 

Partners

Liverpool School of Tropical Medicine

Funders

Bill and Melinda Gates Foundation

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016