Fighting against dengue vectors using the current successful vector control tools (Long Lasting Insecticidal Nets and Indoor Residual Spray) and other measures face physiological, operational and financial challenges such as emergence of insecticide resistance, vector biting time and economic constrains. This underlines the importance of investigating new control interventions against Ae. aegypti (dengue vector) which will synergistically work with the present control tools. We therefore propose to evaluate the potential of attractive toxic sugar-baited resting places (ATSB-RPs) for control of Aedes aegypti in urban Tanzania. To achieve this, a series of experiments will be conducted in a laboratory to determine the ivermectin (IVM) dose required to kill 90% of Aedes. Upon determination of the IVM dose; we will investigate Aedes response to sugar baits even if the host is constantly made available in a semi field system followed by evaluating the effectiveness of the intervention against wild Aedes.
Table1. Illustration of “Aedes aegypti feeding choice between sugar and host blood meal” The baits and rabbits will be placed into the large cages in which the pupae will be released then after emerging they will choose the meal of their choice among the two meals. The blue coloured bait will be introduced into the cage 24 hours before scoring results so as to determine the day that Ae.aegypti fed on sugar solution after emerging and know the gonotrophical stage that Ae.aegypti are likely to take sugar meal