Large-scale (Phase III) evaluation of survivorship, biological efficacy, fabric integrity and community acceptability of DawaPlus 2.0 long-lasting insecticidal nets compared with PermaNet 2.0 in Tanzania
To maximise the efficacy of malaria control using bednets it is essential to understand the effective life of Long-Lasting Insecticidal Nets (LLINs): that is the cost per year of protection that they provide. New brands of LLINs require field evaluation before they are recommended for use in malaria vector control. As net wear differs greatly between regions, nation-wide evaluations of LLINs are required. There are also differences in net products that vary in material, insecticide, or fibre impregnation technology. Such differences are still largely unknown and direct comparisons within sites are scarce. To maintain a range of LLINs there is an urgent need to organize 3-year long prospective studies of LLIN efficacy. We are undertaking a Phase III (household randomized) evaluation of DawaPlus LLINs according to standard WHO guidelines and procedures and LLIN durability guidelines. in which we will measure three outcomes: 1) insecticidal activity, 2) fabric integrity 3) survivorship and 4) community acceptability of DawaPlus 2.0 with PermaNet 2.0 LLINs over three years of use by the households under field conditions in Kilombero.