Targeting residual malaria vectors in areas...

In the News

Study establishes link between gender, extramarital affairs and HIV

Dar es Salaam. A new Ifakara Health Institute study has found “a significant association between lifetime (proxy) extramarital affairs and HIV infection among women only,” with the risk being significantly …

IHI names winners of research, innovation fund

[Right-Left] Getrud, Beatrice, Theckla, and Tutu.Ifakara Health Institute (IHI) has named recipients of the 2017/18 Director’s Research and Innovation Fund. This is an internal funding mechanism aimed to support specific …

Recent Projects

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Demonstrating complete disruption of residual malaria transmission by eliminating Anopheles funestus mosquitoes from rural Tanzanian villages

In rural south-eastern Tanzania, where malaria prevalence has reduced by >60% since 2000, low-to-moderate transmission still persists despite very high coverage with long-lasting insecticidal bednets. Like in most residual transmission …

Targeting residual malaria vectors in areas where long-lasting insecticide treated nets are already widely used

Common malaria interventions, notably insecticidal bed nets have significantly reduced disease, by tackling important malaria mosquitoes, especially those that bite people indoors and rest indoors. However, malaria still causes nearly 430,000 deaths annually, mostly African children. This persistent malaria is increasingly acquired from mosquitoes that bite people outside dwellings, can survive on blood from other vertebrates like cattle, are not readily controlled by indoor interventions like bed nets, and are not easily detectable by existing traps.

residual-malaria-curve-22

Vector surveillance still relies on dangerous and costly methods involving human volunteers; so first, we should introduce simpler, safer and scalable methods. Second, we still do not adequately understand many of these residual mosquitoes, because existing sampling strategies do not capture their atypical behaviours. Lastly, we need more targeted resource allocation, especially since residual transmission is often unevenly distributed. The aim of this project is to develop a low-cost strategy for monitoring densities and transmission activity of residual vector populations that perpetuate malaria transmission in communities where LLINs are widely used, so as to improve targeting of interventions towards elimination. The work also includes demonstrating effective replacement for human volunteers in mosquito surveillance and developing low-cost strategies for large-scale longitudinal monitoring. The field data is then extrapolated using cutting-age mathematical approaches originally developed by theoretical ecologists, to target residual vectors.

Lead Scientists:

Fredros Okumu

Halfan Ngowo

Partners

Liverpool School of Tropical Medicine
Swiss Tropical and Public Health Insitute
University of Glasgow

Funders

Wellcome Trust

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016