Measuring residual malaria transmission in East...

In the News

Scientists: Target TB interventions on these transmission hotspots

(Dar es Salaam, September 14, 2017). Scientists at Ifakara Health Institute (IHI) have recently adapted a method for identifying tuberculosis (TB) transmission hotpots using a new technique that could revolutionize …

Research Office, Lab Technicians required

IHI is looking for suitably qualified Research Officer and Laboratory Technicians to fill vacant positions in the Laboratory Unit in Bagamoyo. To apply or share, get more details about these …

Recent Projects

Understanding and enhancing approaches to quality improvement in small and medium sized private facilities in sub-Saharan Africa

This is an evaluation study that IHI is conducting in collaboration with London school of hygiene and tropical medicine. The research takes place in the context of an innovative intervention …

Vaccine Delivery Costing Study

As countries drive towards achieving high and equitable coverage of life-saving vaccines, the availability of sustainable, equitable, and predictable financing for vaccine delivery is essential. Over the last two decades, …

Investigating the magnitude and drivers of persistent Plasmodium infections in East and West Africa

The global malaria burden has dramatically decreased in recent years, with at least four million fewer deaths today compared to 2001. WHO has estimated that between 2000 and 2015, the annual rate of new malaria cases dropped by 37% globally, and malaria death rates fell by 60%. Current vector control practices, notably long-lasting insecticide treated nets (LLINs) and indoor residual sprays (IRS) have contributed to a significant proportion of this reduction, but the progress is now leveling off, as these interventions are reaching their fundamental protective limits. In many settings, low-level residual transmission now persists even where LLIN and IRS coverage already exceeds 80%. This problem is compounded by the widespread lack of accurate data on the extents and drivers of this residual transmission. We have identified two critically urgent needs associated with this phenomenon as follows: First, it is essential to exhaustively investigate the actual magnitude of the residual malaria transmission, and characterize it on the basis of where and when it occurs, as well as its main environmental and anthropological determinants in different ecological and epidemiological settings. Second, we need complementary interventions, and improved surveillance-response strategies, to effectively target the residual transmission and monitor progress towards elimination. We will rapidly and exhaustively address the first of the above concerns, and then make actionable recommendations for the second. The main objective of this study is therefore to quantify and characterize existing residual Plasmodium transmission in communities where LLINs are already widely used, but where transmission still persists. In the short-term, we will deliver a set of profiles and quantifications of residual malaria transmission and its associated determinants in selected sites in Burkina Faso and Tanzania.  This will then enable effective targeting for malaria elimination. To achieve this main aim, we will pursue the following specific activities.

Lead Scientists:

Marceline (lina) Finda

April Monroe

Fredros Okumu

Partners

World Health Organization
Institute de Reserche en Sciences de la Sante (IRSS)

Funders

World Health Organization

Projects Location

A PIXELBASE DESIGN
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