Using protein labels for entomological investigations...

In the News

Vacancy: Research Scientist (2 posts)

IHI is looking for experienced Research Scientists to work with a project bearing the title: Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA) funded by the UNITAID. This project …

It’s World Malaria Day today: We’re for “Zero malaria”

We’re for “Zero malaria” (Dar es Salaam, April 25 2019) It’s World Malaria Day today. IHI joins with the Ministry of Health, Community Development, Gender, Elderly and Children through the …

Recent Projects

Calcium supplementation on pregnant women

Project summary This is a trial-based study funded by the Bill and Melinda Gates Foundation. It intends to generate evidence for decision-making on the potential non-inferiority of a lower dose …

Sustainable, Healthy, Learning Cities and Neighbourhoods

The Sustainable, Healthy, Learning Cities and Neighbourhoods is an exciting project in which IHI works with a consortium of partners from Asia and Africa to 1) develop capacity for improved …

Protein labels for quantifying exposure of malaria vectors to mosquito control tools and selecting new vector control strategies for development

Using food proteins to label malaria mosquitoes: Long lasting insecticidal nets (LLINs) and indoor residual sprays (IRS) have reduced the burden of malaria but residual transmission still persists. This is because of limitations in the vector population coverage these interventions achieve. New interventions are needed to complement LLINs and IRS but the challenge facing development, selection and optimization of these new vector control tools is the lack of methods to comparatively assess interventions and intervention-combinations to maximize coverage of vector populations. The best tools could be identified, and compared with each other, by measuring what proportion of a mosquito population contacts a given prototype control device or insecticide-treated surface, and whether this targeted fraction of the mosquito population is the same or different from that already targeted by LLINs or IRSs

This project aims at using widely-available and affordable crude sources of detectable proteins from food, such as milk, soybeans, and eggs to label mosquitoes when they contact vector control tools. This technique will enable us to quantify the coverage of existing and new vector control tools, and provide a mechanism to identify the most complementary tools with which to supplement LLINs and IRS to further reduce malaria transmission by filling in gaps in coverage of targeted vector populations

Lead Scientists

Deogratius Roman Kavishe

Gerry F. Killeen

Nicodem Govella

Partners

Liverpool School of Tropical Medicine

Funders

Wellcome Trust

Projects Location

A PIXELBASE DESIGN
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