Using protein labels for entomological investigations...

In the News

Study establishes link between gender, extramarital affairs and HIV

Dar es Salaam. A new Ifakara Health Institute study has found “a significant association between lifetime (proxy) extramarital affairs and HIV infection among women only,” with the risk being significantly …

IHI names winners of research, innovation fund

[Right-Left] Getrud, Beatrice, Theckla, and Tutu.Ifakara Health Institute (IHI) has named recipients of the 2017/18 Director’s Research and Innovation Fund. This is an internal funding mechanism aimed to support specific …

Recent Projects

Development of a new tool for malaria mosquito surveillance to improve vector control

Malaria transmission is influenced not only by vector abundance, but as well by demographic traits such as vector species and age structure, as these influence the intensity by which the …

Demonstrating complete disruption of residual malaria transmission by eliminating Anopheles funestus mosquitoes from rural Tanzanian villages

In rural south-eastern Tanzania, where malaria prevalence has reduced by >60% since 2000, low-to-moderate transmission still persists despite very high coverage with long-lasting insecticidal bednets. Like in most residual transmission …

Protein labels for quantifying exposure of malaria vectors to mosquito control tools and selecting new vector control strategies for development

Using food proteins to label malaria mosquitoes: Long lasting insecticidal nets (LLINs) and indoor residual sprays (IRS) have reduced the burden of malaria but residual transmission still persists. This is because of limitations in the vector population coverage these interventions achieve. New interventions are needed to complement LLINs and IRS but the challenge facing development, selection and optimization of these new vector control tools is the lack of methods to comparatively assess interventions and intervention-combinations to maximize coverage of vector populations. The best tools could be identified, and compared with each other, by measuring what proportion of a mosquito population contacts a given prototype control device or insecticide-treated surface, and whether this targeted fraction of the mosquito population is the same or different from that already targeted by LLINs or IRSs

This project aims at using widely-available and affordable crude sources of detectable proteins from food, such as milk, soybeans, and eggs to label mosquitoes when they contact vector control tools. This technique will enable us to quantify the coverage of existing and new vector control tools, and provide a mechanism to identify the most complementary tools with which to supplement LLINs and IRS to further reduce malaria transmission by filling in gaps in coverage of targeted vector populations

Lead Scientists

Deogratius Roman Kavishe

Gerry F. Killeen

Nicodem Govella


Liverpool School of Tropical Medicine


Wellcome Trust

Projects Location

© Ifakara Health Institute (IHI), 2016