Using protein labels for entomological investigations...

In the News

August CED message is here

Setting smart annual operational objectives The latest monthly message from IHI Chief Executive Director, Dr. Honorati Masanja, is here. This month the director underlines the setting of smart annual operational …

Vacancy: IHI recruits Project Manager for malaria vaccine trials

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Recent Projects

Understanding and enhancing approaches to quality improvement in small and medium sized private facilities in sub-Saharan Africa

This is an evaluation study that IHI is conducting in collaboration with London school of hygiene and tropical medicine. The research takes place in the context of an innovative intervention …

Vaccine Delivery Costing Study

As countries drive towards achieving high and equitable coverage of life-saving vaccines, the availability of sustainable, equitable, and predictable financing for vaccine delivery is essential. Over the last two decades, …

Protein labels for quantifying exposure of malaria vectors to mosquito control tools and selecting new vector control strategies for development

Using food proteins to label malaria mosquitoes: Long lasting insecticidal nets (LLINs) and indoor residual sprays (IRS) have reduced the burden of malaria but residual transmission still persists. This is because of limitations in the vector population coverage these interventions achieve. New interventions are needed to complement LLINs and IRS but the challenge facing development, selection and optimization of these new vector control tools is the lack of methods to comparatively assess interventions and intervention-combinations to maximize coverage of vector populations. The best tools could be identified, and compared with each other, by measuring what proportion of a mosquito population contacts a given prototype control device or insecticide-treated surface, and whether this targeted fraction of the mosquito population is the same or different from that already targeted by LLINs or IRSs

This project aims at using widely-available and affordable crude sources of detectable proteins from food, such as milk, soybeans, and eggs to label mosquitoes when they contact vector control tools. This technique will enable us to quantify the coverage of existing and new vector control tools, and provide a mechanism to identify the most complementary tools with which to supplement LLINs and IRS to further reduce malaria transmission by filling in gaps in coverage of targeted vector populations

Lead Scientists

Deogratius Roman Kavishe

Gerry F. Killeen

Nicodem Govella

Partners

Liverpool School of Tropical Medicine

Funders

Wellcome Trust

Projects Location

A PIXELBASE DESIGN
© Ifakara Health Institute (IHI), 2016